发明名称 GUANINE HAVING A PHOSPHO LIGAND
摘要 Compounds of formula (I), and pharmaceutically acceptable salts thereof <CHEM> wherein R1 is hydroxy, amino, chloro or OR7 wherein R7 is C1-6 alkyl, phenyl or phenyl C1-2 alkyl either of which phenyl moieties may be substituted by one or two substituents selected from halo, C1-4 alkyl or C1-4 alkoxy; R2 is amino or, when R1 is hydroxy or amino, R2 may also be hydrogen; R3 is hydrogen, hydroxymethyl or acyloxymethyl; R4 is a group of formula: <CHEM> R5 and R6 are independently selected from hydrogen, C1-6 alkyl and optionally substituted phenyl; or R3 and R4 together are: <CHEM> wherein R6 is as defined above; having antiviral activity, to processes for their preparation and their use as pharmaceuticals.
申请公布号 AU617724(B2) 申请公布日期 1991.12.05
申请号 AU19880026311 申请日期 1988.11.28
申请人 BEECHAM GROUP P.L.C. 发明人 MICHAEL RAYMOND HARNDEN;DAVID MALCOLM DUCKWORTH
分类号 A61K31/665;A61K;A61K31/675;A61P31/12;A61P35/00;C07F;C07F9/40;C07F9/6506;C07F9/6512;C07F9/6561 主分类号 A61K31/665
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