发明名称 |
Pharmacologically active CNS compounds. |
摘要 |
<p>The invention provides compounds of formula (I) <CHEM> wherein at least one of R<1>, R<2> and R<3> is chloro and the others are selected from hydrogen and chloro; and R<4> and R<5> are the same or different and are each alkyl or hydrogen. The compounds may be used for the treatment or prophylaxis of a neurodegenerative of other neurological disorder of the CNS, the aetiology of which includes excessive release of the neurotransmitter glutamate.</p> |
申请公布号 |
EP0459829(A1) |
申请公布日期 |
1991.12.04 |
申请号 |
EP19910304962 |
申请日期 |
1991.05.31 |
申请人 |
THE WELLCOME FOUNDATION LIMITED |
发明人 |
LEACH, MICHAEL JOHN, THE WELLCOME RESEARCH LAB.;NOBBS, MALCOLM STUART, THE WELLCOME RESEARCH LAB. |
分类号 |
A61P25/00;A61K31/53;A61K31/55;A61P9/10;A61P25/04;A61P25/18;A61P25/24;A61P25/26;A61P25/28;C07D253/06;C07D253/075 |
主分类号 |
A61P25/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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