BENZOTHIOPYRANO(4,3-C)PYRIDAZINE COMPOUNDS, METHODS FOR PREPARING SAID COMPOUNDS AND USES OF SAID COMPOUNDS

摘要

A benzothiopyrano¢4,3-clpyridazine compound of the formula: (I) wherein R1 and R2 are the same or different and each is hydrogen, halogen, trifluoromethyl, hydroxy, amino, nitro, cyano, C1-4 alkyl, C1-4 alkoxy or C2-5 alkanoylamido, R3 is hydrogen, C1-10 alkyl, hydroxy-C1-4 alkyl, C2-5 alkanoyloxy C1-4 alkyl, pyridyl, aryl, aryl-C1-4 alkyl, or substituted aryl or aryl-C1-4 alkyl by at least one substituent selected from the group consisting of halogen, trifluoromethyl, hydroxy, hydroxy, amino, nitro, cyano, C1-4 alkyl, C1-4 alkoxy and C2-5 alkanoylamido on the aromatic ring, n is 0, 1 or 2, and the bond ---- between the 4-position and the 4a-position is single bond or double bond, a method thereof and a use thereof. The compounds possess anti-anxietic activity and are useful as drugs.