发明名称 BENZIMIDAZOLYLPYRIDAZINONES
摘要 Benzimidazolylpyridazinones New benzimidazolylpyridazinones of the formula I in which R1 is a styryl or mononuclear of binuclear hetero aryl radical which contains 1-4 heteroatoms, each of which is unsubstituted or singly or multiply substituted by alkyl, alkoxy, alkylthio, halogen, OH, SH, amino, alkylam;no, dialkylamino, acylamino having 1 - 8 C atoms, nitro, COOH, COOalkyl and/or CN, R2, R3, R4 and R5 are each H or alkyl, and R6 and R7 are each H, or together are a C-C bond, and in which the alkyl and alkoxy groups each contain 1 - 4 C atoms, and their salts, show positive inotropic, vasodilat;ng and antithrombotic actions.
申请公布号 CA1292741(C) 申请公布日期 1991.12.03
申请号 CA19860502035 申请日期 1986.02.17
申请人 MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG 发明人 PRUECHER, HELMUT;JONAS, ROCHUS;PIULATS, JAIME;KLOCKOW, MICHAEL
分类号 A61K31/44;A61K31/4427;A61K31/443;A61K31/4433;A61K31/50;A61P7/02;A61P9/04;A61P9/08;C07D237/00;C07D333/00;C07D401/14;C07D403/04;C07D403/14;C07D405/14;C07D409/14;C07D413/14;C07D417/14 主分类号 A61K31/44
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