发明名称 |
INHIBITION OF INTERLEUKIN-1 BY MONOCYTES AND/OR MACROPHAGES |
摘要 |
A method of inhibiting the production of interleukin-1 by monocytes and/or macrophages in a human in need thereof which comprises administering to such human an effective interleukin-1 production inhibiting amount of a diaryl-substituted imidazole fused to a thiazole, pyrrolidine or piperidine ring or a pharmaceutically acceptable salt thereof. |
申请公布号 |
CA1292694(C) |
申请公布日期 |
1991.12.03 |
申请号 |
CA19870544320 |
申请日期 |
1987.08.12 |
申请人 |
BENDER, PAUL E. |
发明人 |
BENDER, PAUL E.;GRISWOLD, DON E.;HANNA, NABIL;LEE, JOHN C. |
分类号 |
C07D487/04;A61K31/415;A61K31/435;A61K31/44;A61K31/445;A61P29/00;A61P43/00;C07D471/04;C07D513/04 |
主分类号 |
C07D487/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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