发明名称 |
Transdermal therapeutical system comprising physostigmine as active component and process for the production thereof |
摘要 |
The invention relates to a transdermal therapeutic system for the administration of physostigmine onto the skin, composed of a backing layer which is impermeable to the active ingredient, of an active ingredient depot having at least one auxiliary with supportive and distributive function in the form of a sheet-like textile material, of a matrix surrounding the latter on all sides and, where appropriate, of a protective layer which can be detached again, the matrix of which contains 10 - 90 % by weight of polymeric material selected from the group consisting of acrylate- and/or methacrylate-based polymers and esters of hydrogenated rosin, 0 - 30 % by weight of plasticisers based on hydrocarbons and/or esters, and the active ingredient depot contains 15 to 85 % by weight of a 0.1 to 70 % by weight physostigmine solution immediately after manufacture. |
申请公布号 |
PH25852(A) |
申请公布日期 |
1991.12.02 |
申请号 |
PH19530000397 |
申请日期 |
1989.12.20 |
申请人 |
LTS LOHMANN THERAPIE-SYSTEME GMBH & CO. KG |
发明人 |
HILLE, THOMAS, DR.;HOFFMAN, HANS-RAINER, DR.;HUBER, HANS-JOACHIM, DR.;KNOCH, AXEL, DR.;STANISLAUS, FRITZ, DR.;SCHNEIDER, GERHARD, DR. |
分类号 |
A61M37/00;A61K9/70;A61K31/40;A61K47/12;A61L15/16;A61L15/58;A61P25/28 |
主分类号 |
A61M37/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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