PHARMACOLOGICALLY ACTIVE CNS COMPOUNDS

摘要

PHARMACOLOGICALLY ACTIVE CNS COMPOUNDS The invention provides a series of compounds of formula (I) (I) and salts thereof, wherein for example, R1 and R2, which may be the same or different each represent -NR13R14 where R13 and R14 may each independently represent hydrogen or alkyl or, taken together with the nitrogen atom to which they are attached form a heterocyclic ring, optionally substituted by one or more alkyl or arylalkyl groups and optionally containing a further heteroatom; R3 is hydrogen, haloalkyl, alkoxymethyl or alkyl; R4 is hydrogen, nitro or halo; R5 is hydrogen or halo; R6 is hydrogen, halo, nitro, amino, alkylamino or dialkylamino; R7 is hydrogen or halo; R8 is hydrogen or halo; The compounds may be used for the treatment or prophylaxis of a neurodegenerative or other neurological disorder of the CNS, the aetiology or which includes excessive release of the neurotransmitter glutamate. PA1156/