EPITOPES OF THE PRE-S REGION OF HEPATITIS B VIRUS SURFACE ANTIGEN

摘要

Polypeptides corresponding in amino acid residue sequence to native T cell epitopes in the pre-S (2) region of HBsAg are disclosed. A method of mitigating nonresponsiveness to HBsAg comprising including T cell epitopes of both the d and the y subtypes is also disclosed.