发明名称 |
PROCESS FOR L-DOPA |
摘要 |
2189S/1040A 17268 . TITLE OF THE INVENTION PROCESS FOR L-DOPA A process for the preparation of (S)- or L-3-(3,4-dihydroxyphenyl)alanine (L-dopa) is described. The process utilizes water as reaction process solvent and proceeds via formation of an intermediate which can be kinetically resolved in a polar solvent to a precursor of the desired isomer and in which the undesired isomer can be efficiently racemized for reuse. |
申请公布号 |
CA1292478(C) |
申请公布日期 |
1991.11.26 |
申请号 |
CA19870544844 |
申请日期 |
1987.08.19 |
申请人 |
MERCK & CO., INC. |
发明人 |
REINHOLD, DONALD F.;UTNE, TORLEIF;ABRAMSON, NEWTON L. |
分类号 |
C07C227/24;C07C227/12;C07C229/34;C07C229/36 |
主分类号 |
C07C227/24 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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