| 摘要 |
<p>PURPOSE:To advantageously obtain the subject compound by adding a carbonyl compound to a samarium complex obtained from a reaction of an organic halide, aromatic isonitrile and a salt of divalent samarium at a specific condition and reacting with acetic anhydride or water. CONSTITUTION:A compound expressed by the formula RX<1> (R is organic group; X<1> is Cl or Br) is reacted with a compound expressed by the formula R<0>CN (R<0> is aromatic group having substituting group at least one ortho-position, preferably 2,6-xylyl) and a salt expressed by the formula SmX2 2 (X<2> is Cl, Br or I) in a nonprotonic solvent in the presence of hexamethylphosphoramide to obtain a samarium complex and resultant complex is reacted with a compound expressed by formula I (R<1> and R<2> are H or organic group) to obtain a carbonyl compound adduct. Then, said adduct is reacted with a compound expressed by the formula R3 2 O (R<3> is H or acetyl) to advantageously afford the aimed compound expressed by formula II using a samarium complex as an equivalent body of acyl anion without requiring reactions of multi-stage.</p> |
