发明名称 IMPROVED PROCESS FOR (1H)-ISOINDOLIN-1-ONE-3-CARBOXYLIC ACID
摘要 <p>A process for preparing [1H]-isoindolin-1-one-3-carboxylic acid comprising the steps of 1) reacting phthaladehydic acid in an alkanol with ammonia, 2) contacting the resulting solution with an alkali metal cyanide, 3) removing the alkanol, 4) adjusting the pH to 1.0, 5) heating the resulting reaction mixture until product formation is substantially complete and isolating the product.</p>
申请公布号 GR3000882(T3) 申请公布日期 1991.11.15
申请号 GR19900400698T 申请日期 1990.09.27
申请人 PFIZER INC. 发明人 LOWE, JOHN ADAMS, III
分类号 C07D209/46;(IPC1-7):C07D209/46 主分类号 C07D209/46
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