| 摘要 |
<p>A method of diagnosis suitable e.g. for differentiating between hairs of different animals, is adapted to determine the source of a biological structure (e.g. the hair) by hybridising a species-specific probe to single stranded genetic material in situ within said structure whilst maintaining, or substantially maintaining, the integrity thereof. Double stranded genetic material within the structure may be accessed and rendered single stranded, groups are rendered unreactive that react with a polynucleotide probe other than likewise reactive groups comprised by the genetic material, the probe is hybridised with the single stranded genetic material and the structure screened for hybridisation.</p> |
