摘要 |
<p>An antimicrobial compound comprising: <CHEM> wherein Q = phenylene; Y = -H or -methyl; R = -(CF2)yCF3 wherein y = 1 - 20, -(CH2)x-O-CxH2X+1 wherein x = 1 - 25, -(CH2CH2O)n(CH(CH3)CH2O)m (CH2CH(CH3)O)p(CH2CH2O)qT wherein T = -H or a branched or unbranched C1-20 alkyl, n, m, p, q = 0 - 99 and n + m + p + q >/= 1, -CHR'COOH wherein R' is a naturally occurring amino acid side chain, or (CH2)xCOOH; and A = -H, -OH, NH2, -CH2 = CH2, -(CH2CH2O)n(CH(CH3)CH2O)m(CH2CH(CH3)O)p(CH2CH2O)qT, an amine protein linkage, an amine saccharide linkage, a polyhydroxyamine linkage or -COOX wherein X = -H, an amino alcohol moiety, an amino alkoxy silane moiety, -CONH(CH2)xCOOH, or -NHCH2CH-(OX')2 wherein X' = methyl or ethyl. Such novel biocidal compounds may also be combined with proteins and polysaccharides and are stable in a variety of solutions and in a typical biocidal regimen or treatment locus. The biocidal compounds of the invention exhibit an improved antibacterial effect on both gram positive and gram negative bacteria, can have biocidal activity against a variety of other microorganisms including virus, yeast, molds, etc., and can have activity against multi-cellular pests.</p> |