发明名称 PYRROLO[2,3-B]INDOLE-KETONES AND ANALOGS, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS
摘要 This invention relates to pyrrolo[2,3-b]indole ketones of the formula see formula I where R1 is loweralkyl, aryl or arylloweralkyl; R2 is hydrogen, halogen or loweralkyl; R3 is hydrogen or loweralkyl; R4 is loweralkyl or arylloweralkyl; R5 is hydroge n, loweralkyl, loweralkenyl, loweralkynyl, arylloweralkyl, formyl, loweralkylcarbonyl, arylloweralkylcarbonyl or loweralkoxycarbonyl; Y is hydrogen, halogen, loweralkyl or loweralkoxy; the pharmaceutically acceptable addition salts thereof, and whe re applicable, the geometric and optical isomers and racemic mixtures thereof. The compound s of this invention exhibit utility for alleviating various memory dysfunctions such a s Alzheimers disease.
申请公布号 CA2042327(A1) 申请公布日期 1991.11.12
申请号 CA19912042327 申请日期 1991.05.10
申请人 HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED 发明人 ALLEN, RICHARD C.;FLANAGAN, DENISE M.
分类号 A61K31/40;A61K31/407;A61P25/28;C07D209/08;C07D487/04;(IPC1-7):C07D487/04 主分类号 A61K31/40
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