发明名称 LIQUID BISMUTH CONTAINING MEDICINAL PRODUCT, PROCESS FOR PRODUCING IT AND ITS USE
摘要 The invention relates to a liquid, bismuth containing medicinal product for the oral treatment of gastro-intestinal illnesses such as gastritis, ulcers, etc., caused by campylobacter. The invention provides a closed system, e.g. a single dose container or a multiple dose container with dosing device containing one or more portions of the bismuth containing medicinal product. In addition, a simple, inexpensive production process is proposed, in which the bismuth citrate is suspended in water, slightly heated and, accompanied by the addition of caustic potash solution/aqueous ammonia solution, is dissolved and set to a pH-value between 6.0 and 7.0 Subsequently an aqueous tripotassium citrate-citric acid solution is added and if necessary sterilized. The solution obtained is placed in a multidose container with dosing device, or is initially diluted with water to form a ready to drink solution, portioned into single dose containers and optionally sterilized.
申请公布号 US5064857(A) 申请公布日期 1991.11.12
申请号 US19890416922 申请日期 1989.10.04
申请人 R. PFLEGER CHEMISCHE FABRIK GMBH 发明人 BERTHOLDT, HEINZ;MICHALCZYK, DIETER;URBAN, GUENTER
分类号 A61J1/06;A61K9/00;A61K31/29;A61K33/24;A61K47/12;A61P1/12 主分类号 A61J1/06
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