摘要 |
PCT No. PCT/SE91/00221 Sec. 371 Date Dec. 15, 1993 Sec. 102(e) Date Dec. 15, 1993 PCT Filed Mar. 21, 1991 PCT Pub. No. WO91/16352 PCT Pub. Date Oct. 31, 1991.A pyridoxylated hemoglobin is prepared in a one-step, one-container process from red blood cells or essentially stroma-free hemoglobin by suspending the cells or hemoglobin in an aqueous medium, adding a chemical reducing agent and a pyridoxylating agent, and heating the reaction mixture obtained at a certain temperature for a certain time, while maintaining reducing conditions in the reaction medium. |