发明名称 |
PURIFICATION, DETECTION AND METHODS OF USE OF PROTEASE NEXIN-2 |
摘要 |
2079880 9116628 PCTABS00008 Immunopurification of Protease Nexin-2 and .beta. amyloid precursor protein is disclosed. Methods of detecting Protease Nexin-2 and the use of these methods in the diagnosis of Alzheimer's disease and other conditions are also disclosed. Additionally, pharmaceutical preparations including Protease Nexin-2 or modified forms thereof are disclosed. Medical uses for the pharmaceutical preparations are also disclosed. These uses include the treatment and prevention of amyloid plaques in Alzheimer's disease and Down's Syndrome.
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申请公布号 |
CA2079880(A1) |
申请公布日期 |
1991.10.25 |
申请号 |
CA19912079880 |
申请日期 |
1991.03.25 |
申请人 |
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发明人 |
VAN NOSTRAND, WILLIAM E. E.;CUNNINGHAM, DENNIS D.;WAGNER, STEVEN L. |
分类号 |
A61K39/395;C12N5/10;C12N9/99;C12N15/02;C12N15/09;C12P21/02;C12P21/08;C12R1/645;C12R1/91;G01N33/53;G01N33/573;G01N33/577;G01N33/68;G01N33/86;(IPC1-7):C12P21/08;C12N5/18;G01N33/566;A61K38/55;C07K16/38 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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