| 摘要 |
A process for preparing novel corticosteroid intermediates of formula (XXX) are disclosed. The process entails contacting a 9 alpha -hydroxysteroid of formula (XX) with (A) in step (a) an anhydride, an organic acid and an acid reagent having a pKa of about 3 or less, followed by step (b) treatment with water, aqueous alkali or aqueous acid; or alternatively, with (B) either an anhydride and a proton acceptor or with an acyl halide and a proton acceptor, to give the steroid of formula (XXX). By using step (a) in Proces (A), novel steroid intermediates of formula (XXV) are also obtained. |
