NOVEL 4-CHLORO-3-SULFAMOYLBENZOIC ACID HYDRAZIDES, A PROCESS FOR THE PREPARATION THEREOF, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, THEIR USE AS MEDICAMENTS

摘要

The novel compounds according to the invention correspond to the general formula I …… in which… R represents hydrogen, a trifluoromethyl or carboxyl group, an alkoxycarbonyl group having 2-5 carbon atoms, a cyano, benzoyl or sulphamoyl group or an alkylsulphonyl group having 1-4 carbon atoms,… R<1> represents hydrogen, an alkylthio or alkylsulphonyl group each having 1-4 carbon atoms, a straight or branched alkyl group having 1-4 carbon atoms, or a benzylthio, benzylsulphonyl, phenyl, hydroxyl or thiol group and… R<2> represents hydrogen or chlorine. …The novel compounds act as diuretics and saluretics and have a hypotensive action.