TRANSFER AND EXPRESSION OF GENE SEQUENCES INTO CENTRAL NERVOUS SYSTEM CELLS USING HERPES SIMPLEX VIRUS MUTANTS WITH DELETIONS IN GENES FOR VIRAL REPLICATION

摘要

This invention relates to methods of gene delivery to cells in the central nervous system by introducing and expressing gene sequences mediated by herpes simplex virus 1 (HSV-1) vectors with a mutation in a gene for viral replication. A108-08.WP 041690