| 发明名称 |
SUBSTITUTED PYRIMIDINES, PYRIMIDINONES AND PYRIDOPYRIMIDINES |
| 摘要 |
Substituted pyrimidines, pyrimidinones and pyridopyrimidines of formula (I) are as angiotensin II antagonists useful in the treatment of hypertension, ocular hypertension and certain CNS ailments; in the said formula, K is -N(R<8a>)-C(=M) or -N=C(R<8b>) where M is O or NR<22>. |
| 申请公布号 |
WO9115209(A1) |
申请公布日期 |
1991.10.17 |
| 申请号 |
WO1991US01951 |
申请日期 |
1991.03.27 |
| 申请人 |
MERCK & CO., INC. |
发明人 |
ALLEN, ERIC, E.;GREENLEE, WILLIAM, J.;MACCOSS, MALCOLM;PATCHETT, ARTHUR, A. |
| 分类号 |
A61K31/505;A61P9/12;A61P27/02;C07D239/26;C07D239/28;C07D239/36;C07D239/38;C07D239/42;C07D239/46;C07D401/10;C07D401/12;C07D403/10;C07D403/12;C07D471/04;C07F9/6512;C07F9/6518;C07F9/6524 |
主分类号 |
A61K31/505 |
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