发明名称 |
Peptide derivatives with amphiphatic properties, intermediates thereof and liposomes and films comprising said derivatives. |
摘要 |
<p>A peptide derivative amphiphatic compound or N-terminal salt thereof represented by formula (I): <CHEM> wherein R<1> and R<2> each represents a straight-chain or branched alkyl or acyl group having 8 to 24 carbon atoms optionally having a substituent or an unsaturated group; X represents -O-or -NH-; R<3n> and R<3(n+1)> each represents an alpha -amino acid side chain; n is an integer of from 0 to 5; the compound may be a racemic compound or an optically active compound when the compound has an asymmetric carbon atom; and the N-terminal salt of the compound optionally forms with an acid component; an intermediate thereof, a liposome comprising said peptide derivative amphiphatic compound and a film consisting of a monolayer or multilayers comprising the peptide derivative amphiphatic compound are disclosed. <IMAGE></p> |
申请公布号 |
EP0451763(A2) |
申请公布日期 |
1991.10.16 |
申请号 |
EP19910105549 |
申请日期 |
1991.04.08 |
申请人 |
FUJI PHOTO FILM CO., LTD. |
发明人 |
KITAGUCHI, HIROSHI;NEMORI, RYOICHI |
分类号 |
A61K9/127;A61K38/00;B01J13/00;B01J13/02;C07C217/28;C07C219/04;C07C237/08;C07C237/12;C07C237/22;C07K5/06;C07K5/062;C07K5/072;C07K5/08;C07K5/083;C07K5/093;C07K5/10;C07K5/103;C07K7/06;C07K14/705;C07K16/00;C09K3/00 |
主分类号 |
A61K9/127 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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