BENZOQUINOLIZINDERIVATER SAMT FARMACEUTISK ACCEPTABLE SYREADDITIONSSALTE DERAF OG FARMACEUTISK MIDDEL INDEHOLDENDE SAADANNE FORBINDELSER OG DETTES FREMSTILLING

摘要

The invention concerns benzoquinolizines of general formula (I) and their pharmaceutically acceptable acid addition salts. In formula (I), R represents hydrogen or lower alkyl, R1 and R2 which may be the same or different each represent hydrogen, lower alkyl, lower alkoxy or halogen, R3 and R4 which may be the same or different each represents lower alkyl, halo(lower)alkyl or aryl and A represents a lower alkylene group having 1 to 3 carbon atoms in the chain between the two N atoms. The compounds possess alpha 2-adrenoceptor antagonistic activity in warm blooded animals.