| 摘要 |
Novel (((substituted-phenyl)methyl)amino)benzenesulfonic acids having antiviral activity are disclosed. Compounds within the scope of the invention have the formula <IMAGE> wherein R1 represents lower alkyl, lower alkoxy, nitro, amino, cyano, trifluoromethyl, acetyl, methylthio, methylsulfinyl, methylsulfonyl, benzoyl, substituted benzoyl, aminosulfonyl or halogen; and R2 and R3 are the same or different and are selected from the group consisting of hydrogen, lower alkyl, lower alkoxy, amino, cyano, trifluoromethyl, acetyl, methylthio, methylsulfinyl, methylsulfonyl, benzoyl, substituted benzoyl, aminosulfonyl or halogen. The invention also includes the pharmaceutically-acceptable salts of the novel (((substituted-phenyl)methyl)amino)benzenesulfonic acids. Methods of using the compounds as antiviral agents are also disclosed, as well as compositions which comprise a carrier in combination with a suitable antiviral active compound.
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