发明名称 ISOCHROMANE DERIVATIVES
摘要 An isochromane derivative having the general formula I I in which each of R1, R2, and R3 is one to four substituents independently selected from hydrogen, hydroxy, alkyl (1-4 C), alkoxy (1-4 C), halogen, or CF3, or represents a methylenedioxy group; R4 is selected from hydrogen or alkyl (1-4 C); Alk is an alkylene group with 1-4 carbon atoms; Alk' is an alkylene group with 2-4 carbon atoms, when R5 is selected from hydrogen or alkyl (1-4 C) and X is O or S; or Alk' is an alkylene group with 1-4 carbon atoms or a bond, when R5 is an alkyl (1-4 C) group and X is CH2 or a bond; or a pharmaceutically acceptable salt thereof.
申请公布号 CA2039009(A1) 申请公布日期 1991.10.03
申请号 CA19912039009 申请日期 1991.03.25
申请人 AKZO N.V. 发明人 COMBOURIEU, MICHEL;LAIGLE, JEAN-CLAUDE
分类号 A61K31/35;A61K31/352;A61P7/02;A61P9/06;A61P9/08;A61P9/10;A61P9/12;C07D311/76;(IPC1-7):C07D311/76;C07D493/04 主分类号 A61K31/35
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