PRODUCTION OF 2, 4-DICHLORO-3-ETHYL-6-NITROPHENOL

摘要

PURPOSE:To obtain the title high purity compound industrially and advantageously by sulfonating 4-chloro-3-ethylphenol with chlorosulfonic acid in an organic solvent, chlorinating the reaction product and further nitrating the chlorinated substance with nitric acid. CONSTITUTION:4-Chloro-3-ethylphenol which is not required to separate isomers is sulfonated with chlorosulfonic acid in an organic solvent such as a halogenated hydrocarbon to industrially and advantageously give 5-chloro-4- ethyl-2-hydroxybenzenesulfonic acid. Then this compound is chlorinated in a solvent of acetic acid in the presence of sulfur chloride to industrially and advantageously give 3,5-dichloro-4-ethyl-2-hydroxybenzenesulfonic acid. Further, this compound is nitrated with nitric acid to industrially and advantageously give high-purity 2,4-dichloro-3-ethyl-6-nitrophenol useful as an intermediate for cyano coupler for color photography.