| 发明名称 |
LIVE VACCINES LIVE VACCINES |
| 摘要 |
Attenuated microorganism for use in immunoprophylaxis in which the attenuati on is brought about by the presence of a mutation in the DNA sequence of the microorganism which encodes, or which regulates the expression of DNA encoding a pro- tein that is produced in response to environmental stress, the microorganism optionally being capable of expressing DNA encod- ing a heterologous antigen.
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| 申请公布号 |
CA2079463(A1) |
申请公布日期 |
1991.10.01 |
| 申请号 |
CA19912079463 |
申请日期 |
1991.03.28 |
| 申请人 |
WELLCOME FOUNDATION LIMITED (THE) |
发明人 |
DOUGAN, GORDAN;CHARLES, IAN G.;HORMAECHE, CARLOS E.;JOHNSON, KEVIN S.;CHATFIELD, STEVEN N. |
| 分类号 |
A61K39/02;A61K39/112;A61P31/04;C07K14/255;C12N1/21;C12N9/52;C12N15/00;C12N15/09;C12R1/01;C12R1/42;(IPC1-7):C12N1/20 |
主分类号 |
A61K39/02 |
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