发明名称 Fused heterotricyclic imides with psychotropic activity and intermedrates thereof
摘要 There are disclosed compounds of the formula <IMAGE> wherein R1 and R2 taken together represent <IMAGE> R3 and R4 are hydrogen; R5 is 2-pyridinyl, 2-pyrazinyl, 2-pyrimidinyl, 3-pyridazinyl or any of the foregoing R5 moieties substituted by lower alkyl, lower alkoxy, halo lower alkyl, cyano, nitro or halo; X, Y and Z are, independently, N, S, O, NR6, SO, SO2, CR6 or CH2; A is lower alkylene, O or S; R6 is hydrogen, lower alkyl, aryl, aralkyl; m is 3-7; and the pharmaceutically acceptable salts thereof, and their use as antipsychotic/-anxiolytic agents having a low liability for extrapyramidal side effects.
申请公布号 US5053508(A) 申请公布日期 1991.10.01
申请号 US19900491143 申请日期 1990.03.09
申请人 AMERICAN HOME PRODUCTS CORPORATION 发明人 SCHIEHSER, GUY A.;ABOU-GHARBIA, MAGID A.;LIN, CHARLES
分类号 C07D307/93;C07D495/04;C07D498/08 主分类号 C07D307/93
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