发明名称 3-PHENYL-5,6-DIHYDROBENZ(C)ACRIDINE-7-CARBOXYLIC ACIDS AND RELATED COMPOUNDS AS CANCER CHEMOTHERAPEUTIC AGENTS
摘要 Dihydrobenz[c]acridine carboxylic acid derivatives are provided which are useful in treating tumors in mammals. These dihydrobenz[c]acridine carboxylic acid derivatives have the formula: <CHEM> or a pharmaceutically acceptable salt thereof, where R<1>, R<2>, R<3>, R<4> and R<5> are as defined in the specification. Also provided are pharmaceutical compositions of said compounds. In addition, processes for the preparation of these compounds are disclosed.
申请公布号 ZA9000545(B) 申请公布日期 1991.09.25
申请号 ZA19900000545 申请日期 1990.01.25
申请人 THE DU PONT MERCK PHARMACEUTICAL CO. 发明人 CARL HENRY BEHRENS
分类号 C07D219/04;A61K31/47;A61K31/473;A61P35/00;C07D221/18;C07D495/04 主分类号 C07D219/04
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