发明名称 |
Method for modifying the toxicity of DNA reactive cross-linking agents to cells |
摘要 |
The cytotoxicity of DNA reactive cross-linking agents can be modified or reversed by exposing cells exposed to such agents to specific endocytotically absorbed materials. These materials should be capable of interfering with the cross-linking of the DNA. For example, electrophillic materials such as serum proteins, are useful for this purpose.
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申请公布号 |
US5051363(A) |
申请公布日期 |
1991.09.24 |
申请号 |
US19870067190 |
申请日期 |
1987.06.26 |
申请人 |
UNIVERSITY OF PENNSYLVANIA |
发明人 |
RITTER, CARL;RUTMAN, ROBERT J. |
分类号 |
A61K31/13;A61K31/44;A61K33/14;A61K38/38 |
主分类号 |
A61K31/13 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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