摘要 |
<p>The present invention provides a pharmaceutical composition which comprises a pharmaceutically acceptable carrier, a therapeutic agent, and an amout of a barbiturate compound mono-substituted at the carbon-5 position effective to increase retention of the therapeutic agent within a subject. The present invention also provides a method of increasing retention of a therapeutic agent within a subject which comprises administrating to the subject an amount of a barbiturate compound mono-substituted at the carbon-5 position effective to increase the retention of the therapeutic agent within the subject.</p> |