发明名称 |
Therapeutic compositions with controlled release of medicaments supported on crosslinked polymers and coated with polymer films and their preparation process. |
摘要 |
<p>The described therapeutic compositions with controlled release of medicaments comprise a medicament loaded onto particles of a crosslinked non-ionic polymer insoluble but swellable in water, using either swelling with solutions of the medicament or high-energy co-grinding methods. The medicament-loaded particles are coated with a polymers film able to control medicament release, to obtain a prolonged release of the medicament (even exceeding 24 hours) while maintaining high bioavailability.</p> |
申请公布号 |
EP0446753(A1) |
申请公布日期 |
1991.09.18 |
申请号 |
EP19910103224 |
申请日期 |
1991.03.04 |
申请人 |
VECTORPHARMA INTERNATIONAL S.P.A. |
发明人 |
CARLI, FABIO;COLOMBO, ITALO;RABAGLIA, LEONARDO |
分类号 |
A61K9/22;A61K9/14;A61K9/50;A61K9/52;A61K31/13;A61K31/135;A61K31/138;A61K31/165;A61K31/19;A61K31/192;A61K31/196;A61K31/34;A61K31/341;A61K31/40;A61K31/401;A61K31/455;A61K31/52;A61K31/55;A61K31/554;A61K33/14;A61K33/42;A61K45/00;A61K47/32;A61K47/36;A61K47/38;A61K47/40;A61P1/02;A61P1/16;A61P7/10;A61P9/06;A61P9/08;A61P9/10;A61P9/12;A61P25/04;A61P29/00;A61P31/04 |
主分类号 |
A61K9/22 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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