| 摘要 |
Procedure for the preparation of new zinc derivatives of anti-inflammatories with improved therapeutic activity. It is intended for the preparation of new zinc derivatives of formula (I) <IMAGE> where: m can be 1 or 2; q can be 0, 1, 2 or 3; W is a cyclic or heterocyclic radical; and R1 and R2 can be: halogen, carboxyl, lower alkyl or aryl, lower alkoxy or aryloxy, acyl groups, and also cycles or heterocycles, for which the corresponding acid of formula (II) is reacted with an oxide, hydroxide, carbonates or salts of zinc, <IMAGE> or else a corresponding salt of said acid is reacted with a salt of zinc. The reaction takes place in a polar solvent. It is applied for the manufacture of pharmaceutical compounds.
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