发明名称 PROCEDE DE PREPARATION D'HYDROXYALKYL-1 NITRO-5 IMIDAZOLES.
摘要 Process for preparing hydroxyalkyl-1 nitro-5 imidazoles of the general formula (I) by the action of an alkylene oxide on a complex of sulphuric anhydride with a derivative of imidazole of the general formula (II) followed by the acid hydrolysis or alcoholysis of the product obtained. In the general formulae (I) and (II), R is hydrogen, phenyalkyl or phenyl (possibly substitued). In the general formula (I), n is 2 or 3 and one or more carbon atoms of the alkylene chain may be substitued by one or more methyl radicals. In the general formula (II), X is a group which may be eliminated by acid hydrolysis or alcoholysis.
申请公布号 FR2659326(A1) 申请公布日期 1991.09.13
申请号 FR19900003087 申请日期 1990.03.12
申请人 RHONE POULENC SANTE 发明人 LAVIGNE MICHEL;MANDARD-CAZIN BERNADETTE
分类号 C07D233/92;C07D233/93;C07D233/94 主分类号 C07D233/92
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