| 发明名称 |
ACETIC ACID DERIVATIVES |
| 摘要 |
<p>RAN 4045/12 Acetic acid derivatives of the formula H2N(NH)C-X-Y-CO-CH(Q1)COOQ2 I in which X, Y, Z, Q1 and Q2 have the meaning indicated in the description, and hydrates, solvates and physiologically utilisable salts thereof inhibit the binding of adhesive proteins to blood platelets and also inhibit blood platelet aggregation and cell-cell adhesion. They are prepared by removal of protecting groups in appropriate compounds containing ester groups and protected amidino groups.</p> |
| 申请公布号 |
CA2037153(A1) |
申请公布日期 |
1991.09.10 |
| 申请号 |
CA19912037153 |
申请日期 |
1991.02.26 |
| 申请人 |
HOFFMAN-LA ROCHE(F.) CO. AKTIENGESELLSCHAFT |
发明人 |
ALIG, LEO;EDENHOFER, ALBRECHT;MULLER, MARCEL;TRZECIAK, ARNOLD;WELLER, THOMAS |
| 分类号 |
C07K5/097;A01N43/40;A61K;A61K31/195;A61K31/24;A61K31/395;A61K31/40;A61K31/44;A61K31/445;A61K31/495;A61K38/00;A61K38/04;A61K38/06;A61P7/02;A61P9/10;A61P35/00;C07C;C07C227/14;C07C229/32;C07C237/20;C07C237/36;C07C257/18;C07C257/20;C07C271/64;C07D;C07D207/00;C07D207/04;C07D207/08;C07D207/09;C07D207/16;C07D211/34;C07D211/60;C07D211/62;C07D227/04;C07D227/06;C07D241/04;C07D295/185;C07D295/192;C07K;C07K5/00;C07K5/02;C07K5/023;C07K5/06;C07K5/062;C07K5/065;C07K5/072;C07K5/08;C07K5/083;C07K5/093;C07K5/12;C07K14/75;(IPC1-7):C07K5/00 |
主分类号 |
C07K5/097 |
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