Superior pharmaceutical compositions which comprise carriers coupled to epitope-bearing moieties are described. The carriers are crystalline two-dimensional arrays of proteins or glycoproteins, derived from cell envelopes. These conjugates are capable of eliciting the formation of antibodies as well as a T-lymphocyte-mediated immune response following either parenteral or oral administration.
申请公布号
WO9112819(A1)
申请公布日期
1991.09.05
申请号
WO1991CA00063
申请日期
1991.03.04
申请人
CHEMBIOMED, LTD.
发明人
SLEYTR, UWE, B.;MUNDT, WOLFGANG;MESSNER, PAUL;SMITH, RICHARD, H.;UNGER, FRANK, M.;MALCOLM, ANDREW