| 摘要 |
<p>The invention comprises a method for treating tumors in a mammalian patient by administering a combination of a chemotherapeutic agent and a biological response modifier in therapeutically effective amounts to stabilize or substantially reduce the tumor cell load in the mammalian patient. According to the method, a therapeutically effective amount of a chemotherapeutic agent is administered to a mammalian patient, followed by the step of administering the biological response modifier in an amount sufficient to induce substantial terminal differentiation of the residual tumor cells. The biological response modifier comprises natural membrane vesicles and ribosomes in a suspending buffer. The membrane vesicles and ribosomes are derived from a bacterial host. The invention also comprises use of a chemotherapeutic agent and a biological response modifier in the manufacture of a medicament pack for use in the treatment of mammalian tumors.</p> |
