摘要 |
A method of immobilizing a protein on the surface of a support matrix includes the steps of binding the protein to the surface of the support matrix, each of the protein molecules including an active domain. A second molecule is bound to the matrix about the proteins. A dense lattice is formed of the second molecule about the protein to maintain the active domain of the protein exposed away from the surface of the support matrix. A matrix made in accordance with the above method is also disclosed. The matrix includes a support surface and a dense lattice bound to the support surface. The dense lattice includes primary molecules, such as proteins, bound to the support surface. The primary molecules include active domains. Secondary molecules are bound to the support surface about the primary molecules for maintaining the active domains of the primary molecules exposed away from the support surfaces. |