发明名称 STEREOCHEMICALLY CONTROLLED IMMOBILIZATION OF ACTIVE MOLECULES
摘要 A method of immobilizing a protein on the surface of a support matrix includes the steps of binding the protein to the surface of the support matrix, each of the protein molecules including an active domain. A second molecule is bound to the matrix about the proteins. A dense lattice is formed of the second molecule about the protein to maintain the active domain of the protein exposed away from the surface of the support matrix. A matrix made in accordance with the above method is also disclosed. The matrix includes a support surface and a dense lattice bound to the support surface. The dense lattice includes primary molecules, such as proteins, bound to the support surface. The primary molecules include active domains. Secondary molecules are bound to the support surface about the primary molecules for maintaining the active domains of the primary molecules exposed away from the support surfaces.
申请公布号 WO9113358(A1) 申请公布日期 1991.09.05
申请号 WO1991US01094 申请日期 1991.02.19
申请人 BIOQUANT, INC. 发明人 SCHRAMM, WILLFRIED
分类号 G01N33/542;G01N33/543 主分类号 G01N33/542
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