发明名称 |
C-cycloalkyl-alkylamines, process for their preparation, their use as therapeutic agents and intermediates for their synthesis. |
摘要 |
<p>N-Cycloalkylalkylamines of general formula (I) <IMAGE> in which: R1 is a furyl or thienyl radical or is a phenyl radical, provided that Q denotes a 1,2-cyclopropanediyl group, R2 is lower alkyl, R3 is hydrogen or lower alkyl, m has the value 1 or 2, R4 is cycloalkyl -CH(CH2)n, in which n is an integer from 2 to 5, R5 is optionally substituted phenyl or thienyl, Q is 1,2-ethylenediyl or 1,2-cyclopropanediyl, and their addition salts with acids. These amines are psychotropic medications and are also useful in gastroenterology.</p> |
申请公布号 |
EP0445013(A1) |
申请公布日期 |
1991.09.04 |
申请号 |
EP19910400497 |
申请日期 |
1991.02.25 |
申请人 |
JOUVEINAL S.A. |
发明人 |
AUBARD, GILBERT;CALVET, ALAIN;DEFAUX, JEAN-PIERRE;GOURET, CLAUDE-JEAN;GROUHEL, AGNES;HUDSPETH, JAMES;JACOBELLI, HENRI;JUNIEN, JEAN-LOUIS;PASCAUD, XAVIER;ROMAN, FRANCOIS;YUAN, LIN |
分类号 |
A61K31/13;A61K31/135;A61K31/34;A61K31/341;A61K31/38;A61K31/381;A61P1/04;C07C211/27;C07C211/29;C07D307/36;C07D307/52;C07D333/08;C07D333/16;C07D333/20;C07D409/06 |
主分类号 |
A61K31/13 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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