发明名称 HYBRID COMPOUND PURIFICATION
摘要 2077338 9113087 PCTABS00007 A method for purifying from a mixture a hybrid compound which contains a portion of IL-2, which portion includes at least a region of the IL-2R binding domain of IL-2, which region is effective to cause the hybrid compound to bind to cells containing an IL-2R. The method includes passing the mixture containing the hybrid compound over a column having attached thereto molecules consisting of or containing a complex sugar moiety with affinity for the hybrid compound, and eluting the hybrid compound with a suitable eluant. The invention also features related complexes of the hybrid compound and assays for the hybrid compound.
申请公布号 CA2077338(A1) 申请公布日期 1991.09.03
申请号 CA19912077338 申请日期 1991.02.26
申请人 SERAGEN, INC. 发明人 ESTIS, LEONARD F.
分类号 A61K38/00;A61P37/06;C07K1/16;C07K1/22;C07K14/00;C07K14/195;C07K14/52;C07K14/54;C07K14/55;C07K14/76;C07K19/00;G01N30/88;G01N33/68;(IPC1-7):C07K14/55 主分类号 A61K38/00
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