| 发明名称 |
16-HYDROXYMETHYL AMPHOTERICIN B DERIVATIVES |
| 摘要 |
Compounds of formula (I), or pharmaceutically acceptable salts thereof: <CHEM> wherein R1 is -CH2OH; R2 is hydrogen or C1-8 alkyl; R3 is hydrogen or an amine protection group; and each R4 is hydrogen; their preparation, compositions containing them and their use in the treatment of fungal infections are described. |
| 申请公布号 |
ZA8909506(B) |
申请公布日期 |
1991.08.28 |
| 申请号 |
ZA19890009506 |
申请日期 |
1989.12.13 |
| 申请人 |
BEECHAM GROUP PLC |
发明人 |
MICHAEL JOHN DRIVER;WILLIAM SKINNER MACLACHLAN;ANDREW WILLIAM TAYLOR |
| 分类号 |
A61K31/70;A61K31/7042;A61K31/7048;A61P31/04;C07H17/08 |
主分类号 |
A61K31/70 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
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