发明名称 TUMOR NECROSIS FACTOR BINDING PROTEIN
摘要 <p>Tumor Necrosis Factor (TNF) Binding Protein is isolated and substantially purified. It has the ability to inhibit the cytotoxic effect of TNF and/or to maintain its prolonged beneficial effects. TNF Binding Protein II and salts, functional derivatives, precursors and active fractions thereof can be used to antagonize the deleterious effects of TNP and to prolong its beneficial effects Polyclonal and monoclonal antibodies to the TNF Binding Protein II are produced. They be used as pharmaceutical agents and in diagnostic assays.</p>
申请公布号 JPH03197499(A) 申请公布日期 1991.08.28
申请号 JP19900128956 申请日期 1990.05.18
申请人 YEDA RES & DEV CO LTD 发明人 DEBITSUDO UORATSUKU;HARUMUTSUTO ENGERUMAN;DAN ADERUKA;DANIERA NOBITSUKU;MENAKEMU RUBINSUTEIN
分类号 G01N33/53;A61K38/00;A61K38/17;A61K38/19;A61K39/395;A61P37/00;C07K1/14;C07K1/16;C07K1/20;C07K1/22;C07K7/06;C07K14/00;C07K14/435;C07K14/46;C07K14/47;C07K14/52;C07K14/525;C07K14/715;C07K16/00;C07K16/18;C07K16/24;C07K16/28;C12N1/21;C12N5/10;C12N15/09;C12N15/12;C12N15/28;C12N15/63;C12P21/00;C12P21/02;C12P21/08;C12R1/19;C12R1/91;G01N33/564;G01N33/577 主分类号 G01N33/53
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