发明名称 |
TUMOR NECROSIS FACTOR BINDING PROTEIN |
摘要 |
<p>Tumor Necrosis Factor (TNF) Binding Protein is isolated and substantially purified. It has the ability to inhibit the cytotoxic effect of TNF and/or to maintain its prolonged beneficial effects. TNF Binding Protein II and salts, functional derivatives, precursors and active fractions thereof can be used to antagonize the deleterious effects of TNP and to prolong its beneficial effects Polyclonal and monoclonal antibodies to the TNF Binding Protein II are produced. They be used as pharmaceutical agents and in diagnostic assays.</p> |
申请公布号 |
JPH03197499(A) |
申请公布日期 |
1991.08.28 |
申请号 |
JP19900128956 |
申请日期 |
1990.05.18 |
申请人 |
YEDA RES & DEV CO LTD |
发明人 |
DEBITSUDO UORATSUKU;HARUMUTSUTO ENGERUMAN;DAN ADERUKA;DANIERA NOBITSUKU;MENAKEMU RUBINSUTEIN |
分类号 |
G01N33/53;A61K38/00;A61K38/17;A61K38/19;A61K39/395;A61P37/00;C07K1/14;C07K1/16;C07K1/20;C07K1/22;C07K7/06;C07K14/00;C07K14/435;C07K14/46;C07K14/47;C07K14/52;C07K14/525;C07K14/715;C07K16/00;C07K16/18;C07K16/24;C07K16/28;C12N1/21;C12N5/10;C12N15/09;C12N15/12;C12N15/28;C12N15/63;C12P21/00;C12P21/02;C12P21/08;C12R1/19;C12R1/91;G01N33/564;G01N33/577 |
主分类号 |
G01N33/53 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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