DIAZA COMPOUNDS

摘要

Diaza compounds of the formula in which one of the radicals R1 and R2 denotes an aliphatic hydrocarbon radical optionally substituted by halogen or hydroxyl or a cycloaliphatic or araliphatic hydrocarbon radical, the other of the radicals R1 and R2 represents the group of the formula in which Z1 represents alkylene, O, S(O)m or N(R), R5 denotes carboxyl, haloalkanesulphonylamino, SO3H, PO2H2, PO3H2 or 5-tetrazolyl and the rings A and B independently of one another are optionally substituted by an aliphatic hydrocarbon radical which is optionally interrupted by O and optionally substituted by hydroxyl or halogen, hydroxyl which is optionally etherified by an aliphatic alcohol, halogen, carboxyl which is optionally esterified or amidated or 5-tetrazolyl, and either R3 denotes halogen, acyl, an aromatic hydrocarbon radical, carboxyl which is optionally esterified or amidated, cyano, SO3H, PO3H2, PO2H2, 5-tetrazolyl, sulphamoyl which is optionally substituted or acylamino or represents -Z2-R', in which Z2 represents a bond or represents O, S(O)m or N(R) and R' denotes hydrogen or an aliphatic hydrocarbon radical which is optionally interrupted by O or S(O)m and optionally substituted by halogen, hydroxyl, optionally substituted amino or carboxyl which is optionally esterified or amidated, and R4 denotes an aliphatic hydrocarbon radical which is optionally interrupted by O or S(O)m and which is optionally substituted by carboxyl which is optionally esterified or amidated, hydroxyl which is optionally etherified with an aromatic alcohol, optionally substituted amino, S(O)m-R or an aromatic hydrocarbon radical, or R3 and R4 together represent alkylene, where R in each case denotes hydrogen or an aliphatic hydrocarbon radical and m in each case represents 0, 1 or 2, in free form or in the salt form, can be used as pharmaceutical active substances and can be prepared in a manner known per se.