发明名称 |
MACROCYCLIC AMINOPHOSPHONIC ACID COMPLEXES,THEIR PREPARATION FORMULATIONS AND USE |
摘要 |
Particle emitting radionuclides, e.g. Samarium-153, have been complexed with certain macrocyclic aminophosphonic acids wherein the nitrogen and phosphorus are interconnected by an alkylene group or substituted alkylene group. These complexes have been found useful in compositions and formulations for the therapeutic treatment of calcific tumors and the relief of bone pain in animals. |
申请公布号 |
ZA8909734(B) |
申请公布日期 |
1991.08.28 |
申请号 |
ZA19890009734 |
申请日期 |
1989.12.19 |
申请人 |
THE DOW CHEMICAL COMPANY |
发明人 |
JAIME SIMON;DAVID A. WILSON;JOSEPH R. GARLICH;DAVID E. TROUTNER |
分类号 |
C07D257/02;A61K31/395;A61K31/555;A61K51/00;A61K51/04;A61P35/00;C07B59/00;C07F9/38;C07F9/6524 |
主分类号 |
C07D257/02 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|