发明名称 PYRIDINE DERIVATIVES, THEIR PREPARATION AND THEIR USE
摘要 Disclosed are novel pyridine derivatives of the formula (I) where R1 is hydrogen or hydroxyl, R2 is hydroxymethyl, R3 is dimethylaminomethyl, pyrrolidinomethyl, piperidinomethyl or m o r p h o l i n o m e t h y l, or R2 and R3 together may furthermore form the group -CH2-O-CH2-, where a hydrogen atom may be replaced by hydroxyl or methoxy, and R4 is npropyl, isopropyl or n-butyl, and its salts with physiologically tolerated acides. These derivatives are useful for the therapy of cardiac arrhythmias.
申请公布号 CA1288102(C) 申请公布日期 1991.08.27
申请号 CA19860508399 申请日期 1986.05.05
申请人 HEGE, HANS-GUENTHER 发明人 HEGE, HANS-GUENTHER;EISEN, GERHARD;KOENIG, HORST;VON PHILIPSBORN, GERDA
分类号 C07D213/65;A61K31/44;A61K31/4418;A61P9/06;C07D213/66;C07D491/04;C07D491/048 主分类号 C07D213/65
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