NITROFURANTOIN DOSAGE FORM

摘要

NITROFURANTOIN DOSAGE FORM Vikram S. Patel Harry L. Weiles The invention involves a combination sustained release/rapid release pharmaceutical capsule for oral administration of nitrofurantoin comprising, in a capsule shell, a first layer of a first particulate mixture comprising nitrofurantoin, polyvinylpyrrolidone and carboxyvinylpolymer; and a second layer of a second particulate mixture comprising macrocrystalline nitrofurantoin.