| 摘要 |
Compounds of formula (I), in which R1 represents hydrogen, cyano, C2-6 alkanoyl, C2-6 alkoxycarbonyl, CONH2, or R1 represents C1-6 alkyl or C2-6 alkenyl both of which may be substituted by cyano, halo, trifluoromethyl, hydroxy, benzoyl, C2-6 alkanoyloxy, C3-8 cycloalkoxycarbonyl, a 5-7 membered non-aromatic heterocyclic group containing 2 oxygen heteroatoms, CONR9R9', phenoxy or C1-6 alkoxy, in which C1-6 alkoxy may be further substituted by halo, hydroxy, C1-6 alkoxy or C2-6 alkanoyloxy; R2 represents hydrogen or chloro; R3 represents chloro or trifluoromethyl; or R2 and R3 are joined to form a fused benz ring; R4 represents hydrogen, C1-6 alkyl, C1-6 alkoxy or halo; R9 and R9', which may be the same or different represent hydrogen, C1-6 alkyl or benzyl, for use as immunomodulatory agents. |
