C4 BINDING PROTEIN FUSION PROTEINS

摘要

This invention relates to multimeric and hetero-multimeric C4 binding protein (C4bp) fusion proteins and compositions and methods using them. More particularly, this invention relates to multimeric C4bp fusion proteins which are aggregates or assemblies of C4bp monomers linked to functional moieties. It also relates to C4bp fusion polypeptides and in particular CD4-C4bp fusion polypeptides comprising an amino acid sequence for a soluble human CD4 protein fused to a C4bp monomer having, preferably, four short consensus repeat regions.