OPTICALLY ACTIVE 8-METHOXYOUINOLONECARBOXYLIC ACID DERIVATIVES, THEIR PREPARATIVE PROCESSES AND THEIR INTERMEDIATES

摘要

Optically active 8-methoxyquinolonecarboxylic acids repsesented by the formula (I) (I) wherein R1 is lower alkyl have been found to possess potent antibacterial activity against both Gram-negative and Grampositive bacteria. The compounds may be synthesized from novel optically active intermediates.