发明名称 4-METHYL THIAZOLE DERIVATIVES, PREPARATION METHODS THEREFOR AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAID DERIVATIVES
摘要 Novel 4-methylthiazole derivatives, their methods of preparation and the pharmaceutical compositions in which they are present. The present invention relates to novel 4methylthiazole derivatives, to their methods of preparation and to the pharmaceutical compositions in which they are present. According to the invention, these derivatives have the general formula (I) in which n is equal to 0 or 1 and R1 and R2, which are identical or different, are selected from a hydrogen atom, a halogen, a hydroxyl group, a trifluoromethyl group, an alkyl group having from 1 to 4 carbon atoms and an alkoxy group having from 1 to 5 carbon atoms. Application in the treatment of cardiovascular diseases associated with hyperactivity of the sympathetic nervous system.
申请公布号 CA2075998(A1) 申请公布日期 1991.08.20
申请号 CA19912075998 申请日期 1991.02.14
申请人 INSTITUT DE RECHERCHES CHIMIQUES ET BIOLOGIQUES APPLIQUEES (I.R.C.E.B.A.) 发明人 JOBARD-ROUPPERT, FABIENNE;HOUZIAUX, PATRICK;LACOLLE, JEAN-YVES;SAUR, PATRICK;DANREE, BERNARD
分类号 A61K31/425;A61K31/426;A61P25/02;C07D277/20;C07D277/34;C07D417/12;(IPC1-7):C07D417/12;A61K31/495 主分类号 A61K31/425
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