发明名称 |
4-METHYL THIAZOLE DERIVATIVES, PREPARATION METHODS THEREFOR AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAID DERIVATIVES |
摘要 |
Novel 4-methylthiazole derivatives, their methods of preparation and the pharmaceutical compositions in which they are present. The present invention relates to novel 4methylthiazole derivatives, to their methods of preparation and to the pharmaceutical compositions in which they are present. According to the invention, these derivatives have the general formula (I) in which n is equal to 0 or 1 and R1 and R2, which are identical or different, are selected from a hydrogen atom, a halogen, a hydroxyl group, a trifluoromethyl group, an alkyl group having from 1 to 4 carbon atoms and an alkoxy group having from 1 to 5 carbon atoms. Application in the treatment of cardiovascular diseases associated with hyperactivity of the sympathetic nervous system.
|
申请公布号 |
CA2075998(A1) |
申请公布日期 |
1991.08.20 |
申请号 |
CA19912075998 |
申请日期 |
1991.02.14 |
申请人 |
INSTITUT DE RECHERCHES CHIMIQUES ET BIOLOGIQUES APPLIQUEES (I.R.C.E.B.A.) |
发明人 |
JOBARD-ROUPPERT, FABIENNE;HOUZIAUX, PATRICK;LACOLLE, JEAN-YVES;SAUR, PATRICK;DANREE, BERNARD |
分类号 |
A61K31/425;A61K31/426;A61P25/02;C07D277/20;C07D277/34;C07D417/12;(IPC1-7):C07D417/12;A61K31/495 |
主分类号 |
A61K31/425 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|